IAEC

About:  “Institutional Animals Ethics Committee (IAEC)” means a body comprising of a group of persons recognized and registered (Registration number: 878/PO/Re/S/05/CPCSEA) by the Committee for the purpose of control and supervision of experiments on animals (CPCSEA) performed in an establishment which is constituted and operated in accordance with procedures specified for the purpose by the Committee.

Objectives:

(a) Every experiment shall be performed by or under the supervision of a person duly qualified in that behalf, that is, Degree holders in Veterinary Science or Medicine or Laboratory Animal Science of a University or an Institution recognized by the Government for the purpose and under the responsibility of the person performing the experiment;

(b) That experiments are performed with due care and humanity and as far as possible experiments involving operations are performed under the influence of some anesthetic of sufficient power to prevent the animals from feeling pain;

(c) That animals who, in the course of experiments under the influence of anesthetics, are so injured that their recovery would involve serious suffering, are ordinarily medically allowed to death while still under influence of anesthetic;

(d) That experiments on animals are avoided wherever it is possible to do so.

(e) That experiments on larger animals are avoided when it is possible to achieve the same results by experiments on small laboratory animals like guinea-pigs, rabbits, mice, rats etc.

(f) That, as far as possible, experiments are not performed merely for the purpose of acquiring manual skill;

(g) That animals intended for the performance of experiments are properly looked after before, during and after experiments;

(h) That suitable records are maintained with respect to experiments performed on animals

Members

S.No.	Name of IAEC Members	Designations in IAEC
1	Dr. Y. Padmanabha Reddy	Biological Scientist (Chairperson)
2	Dr. P. Ramalingam	Scientist from different discipline (Member Secretary)
3	Dr. B. Srinath	Scientist from different discipline
4	Dr. K. Somasekhar Reddy	Scientist In – charge of Animal House Facility
5	Dr. R. Sarada	Veterinarian
6	Dr. N. Venkata Rami Reddy	Main Nominee
7	Md. Sultan Ali Basha	Link Nominee
8	Dr. R. G. Prakash	Scientist from outside the Institute
9	Dr. Rosa J. Samuel	Socially Aware Nominee

 

Functions

(a) The primary duty of IAEC is to work for achievement of the objectives as mentioned above.

 

(b) IAEC should focus mainly on ensuring ethical and methodical handling of animals during and after experiments, so that they have less suffering.

 

(c) IAEC will review and approve all types of protocols for research involving small animal experimentation before the start of the study.  For approval of experimentation on large animals, the case is required to be forwarded to CPCSEA in prescribed manner with recommendation of IAEC.

(d) IAEC is required to monitor the research throughout the study and after completion of study, IAEC shall obtain the periodic reports on research development and shall ensure visit to animal house facility and laboratory where the experiments are conducted. The committee has to ensure compliance with all regulatory requirements, applicable rules, guidelines and laws.

Recent activities

MINUTES OF THE MEETING

The XVI IAEC meeting of Raghavendra Institute of Pharmaceutical Education and Research, Ananthapuramu was held on 29th December 2020. The study protocols were delivered by investigator (s) through online platform (zoom) at 11:30-1:30 PM in virtual presence of IAEC members. The following protocols were reviewed and necessary corrections were made where ever required in Form B. After ascertaining need and scientific understanding in relevant to the requirement of research, the following protocols were accepted with allowed number of animals to be used.

1. The following protocols has been reviewed and approved by the IAEC.

S.No.	Protocol Number	Title of the project work	Chief Investigator (s)	No. of animals approved
1	IAEC/XVI/01/RIPER/2020	Pharmacological evaluation of various solvent extracts of Lupinus Angustifolius in treating metabolic syndrome in wistar albino rats	Ch. Malathi Suvarna	36 rats
2	IAEC/XVI/02/RIPER/2020	Evaluate the Synergistic effect of Syzygium aromaticum and Elettaria cardamomum against arsenic induced toxicity mouse model	Dr. Vinod Kumar Nelson	36 mice
3	IAEC/XVI/03/RIPER/2020	Safety assessment by toxicity study and In vivo pharmacokinetic study of the developed antimalarial nanophytosomes in rats.	Mr. E. Bhargav	22 rats
4	IAEC/XVI/04/RIPER/2020	In vivo pharmacokinetic study of antihypertensive Telmisartan and Olmesartan medoxomil Nanosuspension  in rats	Mr. E. Bhargav	12 rats
5	IAEC/XVI/05/RIPER/2020	In vivo pharmacokinetic study of acid base neutralized-Olmesartan medoxomil Nanosuspension in rats	Mrs. B. Naga Shubha	12 rats
6	IAEC/XVI/06/RIPER/2020	Treatment of Helicobacter pylori infected rats with floating microspheres	Mr. A. Rajesh Pavan	36 Rats
7	IAEC/XVI/07/RIPER/2020	Investigation of Neuroprotective activity of Andrographis paniculata extract against  Paraquat induced Parkinson’s  mouse model	Dr. Vinod Kumar Nelson	30 mice
8	IAEC/XVI/08/RIPER/2020	Engraftment of human cancers to visualize therapy responses in vivo using adult immunocompromised zebrafish	Dr. P. Ramalingam	96 zebra fishes
9	IAEC/XVI/09/RIPER/2020	Preclinical screening of anti-TB leads from the natural origin in Mycobacterium marinum infected Zebrafish model	Dr. P. Ramalingam	120 zebra fishes
10	IAEC/XVI/10/RIPER/2020	Anti ulcer activity of Opuntia ficus indica against gastric ulcers in rats	Mr. B. Chakrapani	30 rats

2. IAEC members reviewed the earlier approved protocols and expressed their satisfaction
3. IAEC members have provisionally approved the protocol # 8 and advised to contact CPCSEA for further details for importing immunocompromised Zebra fish from NIH, USA.
4. Member secretary concluded the meeting with vote of thanks.